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Retrospective Cohort Study
©The Author(s) 2025.
World J Gastroenterol. Oct 7, 2025; 31(37): 110269
Published online Oct 7, 2025. doi: 10.3748/wjg.v31.i37.110269
Table 3 Factors associated with post-endoscopic retrograde cholangiopancreatography pancreatitis development

Pancreatitis development, n (%)
P value, univariate (χ2 test or Fisher’s exact test, as appropriate)
P value, multivariate binary logistic regression analysis
Multivariate binary logistic regression analysis, objective risk (95%CI)
Elderly patients11/910 (1.4)0.129
Non-elderly patients53/2245 (2.4)
Sex0.1350.1141.498 (0.907-2.475)
Male26/1541 (1.7)
Female40/1606 (2.5)
ASA0.183
1-249/2151 (2.3)
3-417/996 (1.7)
Normal common bile duct0.0230.0371.808 (1.091-1.959)
Yes10/210 (4.8)
No54/2711 (2.0)
Attempts in order to cannulate< 0.0010.0182.015 (1.129-3.596)
< 512/1296 (0.9)
≥ 554/1744 (3.1)
Needle knife use< 0.0010.0182.381 (1.159-4.891)
Yes41/1136 (3.6)
No25/1904 (1.3)
Successful cannulation0.708
Yes64/2921 (2.2)
No2/119 (1.7)
Common bile duct stenting0.239
Yes27/1034 (2.6)
No39/2006 (1.9)
Catheterization of the pancreatic duct0.0260.2801.320 (0.797-2186)
Yes32/1100 (2.9)
No34/2047 (1.7)
Periampulary diverticula0.876
Yes12/592 (2.0)
No54/2448 (2.2)


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