Endoscopic retrograde cholangiopancreatography in elderly patients: Is age just a number or something more?

doi:10.3748/wjg.v31.i37.110269

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Oct 7, 2025; 31(37): 110269
Published online Oct 7, 2025. doi: 10.3748/wjg.v31.i37.110269

Table 1 Epidemiological characteristics, anatomical characteristics and endoscopic retrograde cholangiopancreatography indications in the total cohort and comparison of different age groups, n (%)

	Total cohort	< 80 age old (n = 2245)	≥ 80 (n = 902)	P value
Sex (male/female)	1541 (49)/1606 (51)	1125 (49.9)/1120 (50.1)	416 (46.1)/486 (53.9)	0.044
Age [mean ± SD (min-max)] (years old)	68 ± 16 (17-101) (skewness: -0.892 and kurtosis: 0.282)	62 ± 15 (17-79)	85 ± 4 (80-101)
ASA score				< 0.001
1	540 (17.2)	533 (23.7)	7 (0.8)
2	1611 (51.2)	1228 (54.7)	383 (42.5)
3	984 (31.3)	480 (21.4)	504 (55.9)
4	12 (0.4)	4 (0.2)	8 (0.9)
Antiplatelet use	242 (7.7)	141/2245 (6.3)	101/902 (11.2)	< 0.001
Anticoagulant use	181 (5.8)	95/2245 (4.2)	86/902 (9.5)	< 0.001
Indication				< 0.001
Cholangitis	386 (12.3)	202 (9.0)	184 (20.4)
Obstructive jaundice	910 (28.9)	658 (29.3)	252 (27.9)
Biliary colic	1247 (39.6)	920 (41.0)	327 (36.3)
Pancreatitis	315 (10)	226 (10.1)	89 (9.9)
Bile leak	139 (4.4)	120 (5.3)	19 (2.1)
Asymptomatic choledocholithiasis	150 (4.8)	119 (5.3)	31 (3.4)
Previous gastrectomy	76/3147 (2.4)	46/2245 (2.0)	30/902 (3.3)	0.040
Previous hepatobiliary operation	970/3147 (30.8)	723/2245 (32.2)	247/902 (27.4)	0.008
Periampullary diverticula (among patients in whom Vater ampulla was reached)	617/3085 (20)	374/2205 (17.0)	243/880 (27.6)	< 0.001
Papilla abnormalities (inflamed, impacted stone or adenoma)	501/3040 (16.5)	368/2173 (16.9)	133/867 (15.3)	0.304

ASA: American Society of Anesthesiologists.

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Citation: Voulgaris TA, Tribonias G, Papanikolaou IS, Karamanolis GP, Vezakis IA, Louta A, Varvarelis OP, Chardalias L, Polydorou A, Vezakis A. Endoscopic retrograde cholangiopancreatography in elderly patients: Is age just a number or something more? World J Gastroenterol 2025; 31(37): 110269
URL: https://www.wjgnet.com/1007-9327/full/v31/i37/110269.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i37.110269

Voulgaris TA, Tribonias G, Papanikolaou IS, Karamanolis GP, Vezakis IA, Louta A, Varvarelis OP, Chardalias L, Polydorou A, Vezakis A. Endoscopic retrograde cholangiopancreatography in elderly patients: Is age just a number or something more? World J Gastroenterol 2025; 31(37): 110269 [PMID: 41025009 DOI: 10.3748/wjg.v31.i37.110269]

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