Considerations and clinical utility of referral pathways for early detection of liver disease in at-risk populations

Table 1 Wilson and Jungner criteria for assessing screening eligibility

Wilson and Jungner criteria
Disease	The condition sought should be an important health problem
	The natural history of the condition, including development from latent to declared disease, should be adequately understood
	There should be a recognizable latent or early symptomatic stage
Diagnosis	There should be a suitable test or examination
	The test should be acceptable to the population
	Case-finding should be a continuing process and not a “once and for all” project
Treatment	There should be an agreed policy on whom to treat as patients
	There should be an accepted treatment for patients with recognized disease
Setting	Facilities for diagnosis and treatment should be available
Cost-effectiveness	The cost of case-finding should be economically balanced in relation to possible expenditure on medical care as a whole