Peroxiredoxin 1 inhibits tumorigenesis by activating the NLRP3/GSDMD pathway to induce pyroptosis of colorectal cancer cells

Figure 2 Recombinant peroxiredoxin 1 inhibits the viability of RKO and SW480 cells. A and B: Survival of RKO and SW480 cells detected by MTT under recombinant peroxiredoxin 1 (rPrdx1) stimulation for 24 hours at different doses; C and D: Survival of RKO and SW480 cells detected by MTT under 20 μM rPrdx1 stimulation for different time periods. This experiment was repeated three times in independent experiments. Data are expressed as the mean ± SD; ^aP < 0.05 vs control group (without rPrdx1); ^bP < 0.01 vs control group (without rPrdx1). Prdx1: Peroxiredoxin 1; rPrdx1: Recombinant peroxiredoxin 1.