BPG is committed to discovery and dissemination of knowledge
Review
©The Author(s) 2025.
World J Gastroenterol. Sep 28, 2025; 31(36): 111137
Published online Sep 28, 2025. doi: 10.3748/wjg.v31.i36.111137
Table 1 Convolutional neural network architectures adapted for medical image analysis
Ref.
Architecture
Key strengths
Limitations
Applications
[39]AlexNetIntroduced rectified linear unit, dropout, graphics processing unit accelerationOverfitting on small datasetsHistopathology image classification
[40]VGGNetUniform structure, easy to implementLarge number of parameters, memory-intensivePolyp detection, organ segmentation
[41]GoogLeNetMulti-scale feature extraction, fewer parameters than VGGComplex architecture, harder to modifyLesion classification, colonoscopy image analysis
[42]ResNetResidual connections solve vanishing gradientCan overfit if dataset is smallDetection of GI tumors, segmentation of ulcers
[43]U-NetExcellent for biomedical segmentation, works with few imagesLimited to segmentation tasksPolyp segmentation, mucosal layer delineation
[44]DenseNetStrong gradient flow, parameter-efficientComputationally intensiveEndoscopic image classification, disease grading
[45]Attention U-NetIncorporates attention for better focus on relevant regionsIncreased complexity and longer training timeIBD severity scoring; small bowel bleeding detection
[46]EfficientNetOptimized trade-off between accuracy and speedRequires careful scaling and tuningLightweight, mobile-compatible GI image classification
[47]Swin-CNNWindow-based attention + CNN; balances local and global featuresComplex design; tuning is more demandingGI endoscopy video anomaly detection; GI tumor recognition
[48]TransUNetCombines CNN for feature extraction and Transformer for context modelingResource intensive; slower trainingComputed tomography/magnetic resonance imaging organ segmentation; GI lesion boundary detection
[49]MedT (medical transformer)Pure transformer-based; excellent at long-range dependency modelingNot optimal for small datasets; data hungryIntestinal lesion segmentation; colorectal cancer prediction
[50]ConvNeXtCombines CNN stability with Transformer-like design; efficient trainingRelatively new; limited ecosystem maturityMulti-organ classification; tumor region detection


Write to the Help Desk