Critical flicker frequency improves after alcohol detoxification and is associated with liver stiffness

Table 4 Spearman correlations for critical flicker frequency before and after alcohol detoxification (n = 44)

Parameter	CFF1 (Hz)			CFF2 (Hz)
	r	P value	n	r	P value	n
CFF1 (Hz)	1.00	< 0.001	44	0.59	< 0.001	44
CFF2 (Hz)	0.59	< 0.001	44	1.00	< 0.001	44
Sex (female = 0, male = 1)	0.08	0.586	44	0.15	0.347	44
Age (years)	-0.13	0.385	44	-0.10	0.518	44
Alcohol consumption (g/day)	0.18	0.263	40	0.06	0.717	40
Pack years	-0.10	0.591	30	0.10	0.606	30
BMI (kg/m2)	-0.55	0.015	19	-0.29	0.223	19
AST (U/L)	-0.10	0.530	44	-0.02	0.936	25
ALT (U/L)	0.03	0.829	44	-0.04	0.845	24
GGT (U/L)	-0.22	0.169	39	-0.03	0.886	24
AP (U/L)	0.01	0.947	44	0.02	0.943	25
Bilirubin total (μmol/L)	-0.13	0.419	42	0.18	0.415	23
Quick (%)	0.23	0.136	44	0.23	0.319	20
INR	-0.25	0.105	43	-0.26	0.274	20
Urea (mmol/L)	-0.10	0.544	43	-0.27	0.233	21
Creatinine (μmol/L)	-0.12	0.426	44	-0.31	0.176	21
Sodium (mmol/L)	0.01	0.971	41	-0.53	0.027	17
Potassium (mmol/L)	0.19	0.243	41	-0.26	0.315	17
Lipase (U/L)	-0.13	0.435	39	0.07	0.867	8
PTT (seconds)	0.12	0.681	14	0.09	0.727	17
Hemoglobin (g/L)	0.15	0.344	44	0.19	0.364	25
Hematocrit (%)	0.12	0.432	44	0.14	0.495	25
Erythrocytes (/pL)	0.25	0.096	44	0.09	0.671	25
Leukocytes (/nL)	0.13	0.415	44	-0.31	0.130	25
Platelets (/nL)	0.48	0.001	44	-0.29	0.163	25
Ferritin (μg/L)	-0.22	0.204	35	0.17	0.571	13
CRP (mg/L)	-0.12	0.466	42	0.18	0.451	20
Alcohol (g/L)	-0.02	0.902	38	-0.02	0.937	20
Spleen size (cm)	0.02	0.883	39	0.20	0.221	39
Ascites (1 or 0)	-0.15	0.361	41	-0.25	0.122	41
Steatosis hepatis (0-3)	0.04	0.823	40	0.09	0.595	40
Cirrhosis (1 or 0)	-0.11	0.469	44	-0.13	0.399	44
Liver stiffness (kPa)	-0.04	0.819	35	0.64	0.033	11

CFF1: Critical flicker frequency before alcohol detoxification; CFF2: Critical flicker frequency after alcohol detoxification; BMI: Body mass index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; GGT: Gamma-glutamyl transferase; AP: Alkaline phosphatase; INR: International normalized ratio; PTT: Partial thromboplastin time; CRP: C-reactive protein.