Radiofrequency ablation with or without capecitabine maintenance therapy for lung oligometastases from colorectal cancer

doi:10.3748/wjg.v31.i35.110152

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2025; 31(35): 110152
Published online Sep 21, 2025. doi: 10.3748/wjg.v31.i35.110152

Table 4 Multivariate Cox proportional hazards analysis of the association between whether chemotherapy was combined after radiofrequency ablation and overall survival in colorectal cancer patients with lung metastases

Group	n (total)	n (%)	Crude	Model 1	Model 2	Model 3	Model 4
Only RFA	99	17 (17.2)	1 (Reference)
Combined	148	8 (5.4)	0.35 (0.15-0.81)	0.33 (0.14-0.77)	0.31 (0.13-0.73)	0.29 (0.11-0.77)	0.31 (0.12-0.79)
P value			0.011	0.014	0.008	0.012	0.014

RFA: Radiofrequency ablation; Combined: Radiofrequency ablation plus capecitabine; Only RFA: Radiofrequency ablation alone; Model 1: Adjusted for sex, age; Model 2: Adjusted for model 1 + KRAS + carcinoembryonic antigen; Model 3: Adjusted for model 2 + lesion diameter + distance between the lesion and the mediastinum or great vessels + distance between the lesion and the pleural surface + primary lesion pathology + neural invasion + lymphovascular invasion; Model 4: Adjusted for model 3 + synchronous or metachronous + pneumothorax.

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Citation: Li KN, Ying LL, Du N, Wang Y, Huang HZ, Wang YH, Xu LC, Zhao Q, Song G, Hu YB, Li WT, Yan Y, Chen C, He XH. Radiofrequency ablation with or without capecitabine maintenance therapy for lung oligometastases from colorectal cancer. World J Gastroenterol 2025; 31(35): 110152
URL: https://www.wjgnet.com/1007-9327/full/v31/i35/110152.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i35.110152

Li KN, Ying LL, Du N, Wang Y, Huang HZ, Wang YH, Xu LC, Zhao Q, Song G, Hu YB, Li WT, Yan Y, Chen C, He XH. Radiofrequency ablation with or without capecitabine maintenance therapy for lung oligometastases from colorectal cancer. World J Gastroenterol 2025; 31(35): 110152 [PMID: 41024768 DOI: 10.3748/wjg.v31.i35.110152]

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