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©The Author(s) 2025.
World J Gastroenterol. Sep 14, 2025; 31(34): 110611
Published online Sep 14, 2025. doi: 10.3748/wjg.v31.i34.110611
Table 1 Comparison of key imaging modalities in perianal fistulising Crohn’s disease1

Pelvic MRI
Transperineal ultrasound
Endoanal ultrasound
Fistula detectionGold standard for detecting complex and deep fistula tractsOptimal for superficial and anterior fistula tractsOptimal for simple, low fistula tracts
Abscess detectionCapable of identifying deep and pelvic abscessesCapable of detecting local abscesses, may miss deeper pelvic collectionsCapable of detecting local abscesses, may miss deeper pelvic collections
Assessment of extent of fistula tractProvides extensive pelvic mapping, delineating the full course of fistula tracts and associated complicationsLimited, particularly for supralevator tracts and deeper extensionLimited, confined to anal canal and surrounding tissues
Sphincter involvementVisualises damage and inflammation to sphinctersLimited less detailed visualisation of sphincter complexHigh resolution images of internal and external sphincter anatomy; utility for assessment of sphincter integrity
Pre-surgical planningIdeal for mapping complex fistula anatomy and planning surgical interventionsLimited, assessment of superficial diseaseOptimally reserved for low, simple fistulising disease to aid surgical decision-making
Post-treatment monitoringOptimal for long-term monitoring and assessment of deep healing; not feasible for frequent repetition due to cost and availabilityEasy and repeatable, even at short intervals; useful for monitoring superficial diseaseCapable, but invasive, may not be suitable for frequent use
Patient comfortComfortable, non-invasive; longer examination timeComfortable, non-invasive; requires perineal exposureLess comfortable; involves probe insertion; not suitable in setting of rectal stenosis
AccessMay be limited to high resource healthcare settings May be limited by expertiseMay be limited by expertise
CostHigh Low Moderate; may increase if endoscopy required
Operator dependencyLow to moderate; standardised protocols reduce variabilityHighHigh
AdvantagesComprehensive evaluation of complex anatomy, superior soft tissue contrastNon-invasive, accessible and cost-effective; repeatable at short- and medium- intervalsHigh-resolution imaging of anal sphincter complex, effective for simple fistulas
DisadvantagesHigh cost, resource intensive; difficult to repeat at short intervalsLimited in assessment of deep or complex fistulas; operator dependentInvasive; limited field of view; operator dependent


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