©The Author(s) 2025.
World J Gastroenterol. Sep 14, 2025; 31(34): 110611
Published online Sep 14, 2025. doi: 10.3748/wjg.v31.i34.110611
Published online Sep 14, 2025. doi: 10.3748/wjg.v31.i34.110611
Table 1 Comparison of key imaging modalities in perianal fistulising Crohn’s disease1
| Pelvic MRI | Transperineal ultrasound | Endoanal ultrasound | |
| Fistula detection | Gold standard for detecting complex and deep fistula tracts | Optimal for superficial and anterior fistula tracts | Optimal for simple, low fistula tracts |
| Abscess detection | Capable of identifying deep and pelvic abscesses | Capable of detecting local abscesses, may miss deeper pelvic collections | Capable of detecting local abscesses, may miss deeper pelvic collections |
| Assessment of extent of fistula tract | Provides extensive pelvic mapping, delineating the full course of fistula tracts and associated complications | Limited, particularly for supralevator tracts and deeper extension | Limited, confined to anal canal and surrounding tissues |
| Sphincter involvement | Visualises damage and inflammation to sphincters | Limited less detailed visualisation of sphincter complex | High resolution images of internal and external sphincter anatomy; utility for assessment of sphincter integrity |
| Pre-surgical planning | Ideal for mapping complex fistula anatomy and planning surgical interventions | Limited, assessment of superficial disease | Optimally reserved for low, simple fistulising disease to aid surgical decision-making |
| Post-treatment monitoring | Optimal for long-term monitoring and assessment of deep healing; not feasible for frequent repetition due to cost and availability | Easy and repeatable, even at short intervals; useful for monitoring superficial disease | Capable, but invasive, may not be suitable for frequent use |
| Patient comfort | Comfortable, non-invasive; longer examination time | Comfortable, non-invasive; requires perineal exposure | Less comfortable; involves probe insertion; not suitable in setting of rectal stenosis |
| Access | May be limited to high resource healthcare settings | May be limited by expertise | May be limited by expertise |
| Cost | High | Low | Moderate; may increase if endoscopy required |
| Operator dependency | Low to moderate; standardised protocols reduce variability | High | High |
| Advantages | Comprehensive evaluation of complex anatomy, superior soft tissue contrast | Non-invasive, accessible and cost-effective; repeatable at short- and medium- intervals | High-resolution imaging of anal sphincter complex, effective for simple fistulas |
| Disadvantages | High cost, resource intensive; difficult to repeat at short intervals | Limited in assessment of deep or complex fistulas; operator dependent | Invasive; limited field of view; operator dependent |
- Citation: Habeeb H, Chen L, De Kock I, Bhatnagar G, Kutaiba N, Vasudevan A, Srinivasan AR. Imaging in perianal fistulising Crohn’s disease: A practical guide for the gastroenterologist. World J Gastroenterol 2025; 31(34): 110611
- URL: https://www.wjgnet.com/1007-9327/full/v31/i34/110611.htm
- DOI: https://dx.doi.org/10.3748/wjg.v31.i34.110611