Methotrexate in the management of Crohn’s disease: A practice survey of gastroenterologists in France

Figure 1 Scores used to assess clinical and endoscopic activity of Crohn’s disease. Distribution of scores used by respondents to evaluate clinical and endoscopic activity in Crohn’s disease. Multiple answers were allowed to the question: “What score(s) do you use to assess the clinical and endoscopic activity of Crohn’s disease?” (multiple-choice question). Clinical activity scores assess patient symptoms, well-being, and functional status to guide treatment and monitor disease control: Harvey-Bradshaw index: Simplified clinical index based on general well-being, abdominal pain, number of liquid stools, abdominal mass, and extra-intestinal complications; Crohn’s disease activity index: Comprehensive index incorporating stool frequency, abdominal pain, general well-being, hematocrit, weight, use of anti-diarrheal medication, abdominal mass, and complications. Endoscopic activity scores assess mucosal inflammation and healing via endoscopic examination: Simple endoscopic score for Crohn’s disease: Quantifies ulcers, extent of ulcerated surface, affected surface, and narrowing in ileum and colon; Crohn’s disease endoscopic index of severity: Complex index evaluating deep ulceration, surface involvement, ulcerated surface, and stenosis in various bowel segments; Rutgeerts score: Validated for assessing postoperative recurrence after ileocolonic resection; Its application outside postoperative settings is not validated and should be interpreted with caution. CDAI: Crohn’s disease activity index; CDEIS: Crohn’s disease endoscopic index of severity; SES-CD: Simple endoscopic score for Crohn’s disease.