Early postnatal characteristics and differential diagnosis of choledochal cyst and cystic biliary atresia

doi:10.3748/wjg.v31.i33.108369

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 7, 2025; 31(33): 108369
Published online Sep 7, 2025. doi: 10.3748/wjg.v31.i33.108369

Table 1 Comparison of baseline clinical data between the cystic biliary atresia and choledochal cyst groups

Parameters	CC group (n = 274)	CBA group (n = 45)	P value
Age at surgery (days)	29.0 (21.0, 43.0)	25.0 (18.0,34.0)	0.011
Sex (female/male)	194/79	35/17	0.599
TBA (μmol/L)	16 (5.1, 57.6)	91.4 (60.3, 114.9)	< 0.001
TBIL (μmol/L)	166.1 (104.3, 222.8)	193.1 (165.3, 229.8)	0.019
DBIL (μmol/L)	20.3 (13.0, 41.6)	77.8 (44.0, 97.4)	< 0.001
GGT (U/L)	296.5 (164.2, 580.5)	482.0 (294, 762.0)	0.002
AST (U/L)	37.0 (26.6, 52.1)	81.2 (39.2, 138.8)	< 0.001
ALT (U/L)	17.3 (11.8, 26.4)	35.1 (14.7, 80.4)	< 0.001
LDC (cm)	4.3 (3.0, 5.8)	1.9 (0.8, 2.7)	< 0.001
TDC (cm)	3.2 (2.2, 4.4)	1.4 (0.7, 2.1)	< 0.001

CC: Choledochal cyst; CBA: Cystic biliary atresia; TBA: Total bile acid; TBIL: Total bilirubin; DBIL: Direct bilirubin; GGT: γ-glutamyl transferase; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; LDC: Longitudinal diameter of the cysts; TDC: Transverse diameter of the cysts.

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Citation: Tian Y, Chen S, Ji C, Wang XP, Ye M, Chen XY, Luo JF, Li X, Li L. Early postnatal characteristics and differential diagnosis of choledochal cyst and cystic biliary atresia. World J Gastroenterol 2025; 31(33): 108369
URL: https://www.wjgnet.com/1007-9327/full/v31/i33/108369.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i33.108369

Tian Y, Chen S, Ji C, Wang XP, Ye M, Chen XY, Luo JF, Li X, Li L. Early postnatal characteristics and differential diagnosis of choledochal cyst and cystic biliary atresia. World J Gastroenterol 2025; 31(33): 108369 [PMID: 40933458 DOI: 10.3748/wjg.v31.i33.108369]

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