Noninvasive model based on liver and spleen stiffness for predicting clinical decompensation in patients with cirrhosis

Table 4 Multivariate analysis of parameters in patients with compensated and decompensated cirrhosis

Parameter	Patients with compensatory stage of cirrhosis, n = 72	Patients with decompensation of cirrhosis, n = 68	t/Z	P value
SSM, kPa	23.50 ± 6.1	18.32 ± 4.2	5.866	< 0.001
PLT, × 109/L	110.51 ± 69.1	61.81 ± 25.7	5.463	0.575
LSM, kPa	15.53 ± 5.7	23.86 ± 5.2	-9.023	< 0.001
ALT, IU/L	36.00 (24.00, 47.75)	27.50 (17.00, 42.25)	-2.490	0.597
GGT, IU/L	61.00 (28.00, 120.00)	34.50 (19.25, 59.50)	-3.718	0.566
SLD, mm	12.99 ± 3.0	15.68 ± 3.1	-5.282	0.037
ALB, g/dL	38.69 ± 6.4	34.43 ± 7.4	3.631	0.207
TCHO, mmol/L	3.67 ± 1.3	3.09 ± 0.9	2.939	0.224
PT, seconds	12.08 ± 1.9	13.70 ± 2.5	-4.322	0.480
INR	1.10 ± 0.2	1.24 ± 0.2	-4.029	0.584
PTA,%	84.91 ± 18.9	72.37 ± 17.0	4.123	0.623
PVD, mm	12.03 ± 1.6	13.78 ± 2.4	-5.072	0.773
CTLV, cm3	1055.93 ± 344.8	898.64 ± 257.3	3.045	0.967
CTSV, cm3	519.10 ± 296.0	842.19 ± 416.3	-5.315	0.895

SSM: Spleen stiffness measurement; PLT: Platelet; LSM: Liver stiffness measurement; ALT: Alanine aminotransferase; GGT: Gamma-glutamyl transferase; SLD: Spleen length diameter; ALB: Albumin; TCHO: Total cholesterol; PT: Prothrombin time; INR: International normalized ratio; PTA: Prothrombin activity; PVD: Portal vein diameter; CTLV: Actual liver volume measured by computed tomography; CTSV: Actual spleen volume measured by computed tomography.