Novel chromogenic medium-based method for the rapid detection of Helicobacter pylori drug resistance

Table 5 Comparison of minimum inhibitory concentrations between Columbia medium and characteristic medium (μg/mL)

H. pylori	Columbia medium				Characteristic medium
	LVX	CLR	MTZ	AMX	LVX	CLR	MTZ	AMX
	0.5	0.5	4	0.0625	0.5	0.5	4	0.0625
G27	-	-	-	-	×	×	×	×
26695	-	-	-	-	×	×	×	×
159	+	+	+	+	√	√	√	√
161	+	+	+	+	√	√	√	√
162	+	+	+	+	√	√	√	√
163	+	+	+	+	√	√	√	√
286	+	+	+	+	√	√	√	√
287	+	+	+	+	√	√	√	√
289	+	+	+	+	√	√	√	√
290	+	+	+	+	√	√	√	√

+: Indicates bacterial growth; -: Signifies the absence of bacterial growth; ×: Denotes no bacterial growth and no color change in the medium after 72 hours of incubation. √: Indicates a discoloration observed in the medium after 28-36 hours of incubation. Notably, Helicobacter pylori growth was confirmed after 72 hours of culture. LVX: Levofloxacin; CLR: Clarithromycin; MTZ: Metronidazole; AMX: Amoxicillin; Helicobacter pylori: H. pylori.