Efficacy and safety of different doses of dexmedetomidine on gastrointestinal function recovery after laparoscopic colorectal surgery

Table 2 Comparison of indicators related to surgical and anesthesia among the three groups, mean ± SD/n (%)

Item	Control (n = 281)	Low-dose (n = 313)	High-dose (n = 285)
Site of surgery
Proctectomy	88 (31.32)	96 (30.67)	102 (35.79)
Colectomy	193 (68.68)	217 (69.33)	183 (64.21)
Right hemicolectomy	122 (43.41)	141 (45.05)	113 (39.65)
Left hemicolectomy	61 (21.71)	63 (20.13)	59 (20.70)
Total colectomy	10 (3.56)	13 (4.15)	11 (3.86)
Operation time (minute)	207.97 ± 22.35	210.42 ± 23.03	208.97 ± 22.79
Anesthesia time (minute)	283.80 ± 23.17	285.25 ± 24.06	286.60 ± 25.06
Extubate time (minute)	21.54 ± 4.95	22.29 ± 6.47	23.20 ± 6.65a,1
Dose of dexmedetomidine (μg)	0	69.97 ± 11.71	159.51 ± 27.71a,2
Propofol (mg)	1080.72 ± 197.13	1002.78 ± 184.6a,1	1005.08 ± 183.30a,1
Sufentanil (μg)	27.52 ± 5.41	26.74 ± 5.53	26.18 ± 5.12a,1
Remifentanil (mg)	3.28 ± 0.63	2.67 ± 0.51a,1	2.59 ± 0.50a,1
Cisatracurium (mg)	23.10 ± 2.52	22.89 ± 2.62	23.24 ± 2.73

^aP < 0.05.

¹P compared with the control group.

²P compared with low-dose group.