Age- and gender-specific dynamics and next-generation reference intervals for pepsinogen in northern China

Table 4 Comparison of flagging rates between partitioned and next-generation reference intervals across age groups

Age group, years	PG I				PG II
	URL flagging rate (%)		LRL flagging rate (%)		URL flagging rate (%)		LRL flagging rate (%)
	Partitioned	Continuous	Partitioned	Continuous	Partitioned	Continuous	Partitioned	Continuous
20-29	1.37	2.74	2.74	2.74	0	2.78	2.78	2.78
30-39	1.75	2.34	4.09	3.51	2.96	2.96	2.37	2.96
40-49	3.94	1.97	1.48	2.96	3.4	1.94	1.46	1.94
50-59	3.01	3.76	2.26	1.5	1.43	2.14	3.57	3.57
≥ 60	2.04	2.04	3.06	3.06	4.55	2.73	0.91	1.82
Total	2.65	2.51	2.65	2.95	2.73	2.44	2.15	2.58

The upper reference limit/Lower reference limit flagging rate refers to the percentage of test results fall outside the reference limits. PG: Pepsinogen; LRL: Lower reference limit; URL: Upper reference limit.