Prognostic value of signet-ring cell carcinoma proportion in undifferentiated gastric cancer: Implications for endoscopic treatment decisions

Figure 2 Histologic features of signet ring cell carcinoma groups. Representative hematoxylin and eosin-stained images of gastric carcinoma showing varying proportions of signet-ring cell (SRC) components. The signet ring cell carcinoma (SRCC) group. A: Group 1: SRCC rate < 10%; B: Group 2: 10% ≤ SRCC rate < 50%; C: Group 3: 50% ≤ SRCC rate < 90%; D: Group 4: SRCC rate ≥ 90%. SRCs (arrow) are characterized by intracytoplasmic mucin and eccentrically displaced nuclei, while poorly cohesive carcinoma not otherwise specified cells (arrowhead) lack these features. Original magnification × 200 for all panels.