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©The Author(s) 2025.
World J Gastroenterol. Jul 21, 2025; 31(27): 106166
Published online Jul 21, 2025. doi: 10.3748/wjg.v31.i27.106166
Published online Jul 21, 2025. doi: 10.3748/wjg.v31.i27.106166
Figure 7 Choline-deficient L-amino acid-defined diet-induced model blood count and neutrophil extracellular trap-associated peripheral markers.
A: White blood cell count; B: Lymphocyte count; C: Neutrophil count; D: Concentration of myeloperoxidase; E: Concentration of neutrophil elastase; F: Myeloperoxidase-DNA complex count; G: NETotic neutrophil count; H: Concentration of extracellular DNA (ecDNA); I: DNase activity; J: Concentration of nuclear DNA; K: Concentration of mitochondrial DNA; L: Concentration of small (20-250 bp) fragments of circulating ecDNA; M: Concentration of large (250-1000 bp) fragments of circulating ecDNA; N: Ratio between small and large fragments of circulating ecDNA. Data are presented as mean ± SE (A-M) or standard deviation (N). aP < 0.05; bP < 0.01; cP < 0.001; A-M: Repeated two-way analysis of variance and Bonferroni post-hoc test; N: Independent Student’s t-test. CTRL CSAA: Control group (n = 7); CDAA: Experimental liver steatosis group (n = 10). WBC: White blood cell; LYM: Lymphocytes; NEU: Neutrophils; MPO: Myeloperoxidase; NE: Neutrophil elastase; NET: Neutrophil extracellular trap; ecDNA: Extracellular DNA; ncDNA: Nuclear DNA; mtDNA: Mitochondrial DNA; TAA: Thioacetamide; CTRL CSAA: Choline-sufficient L-amino acid-defined control; CDAA: Choline-deficient L-amino acid-defined.
- Citation: Feješ A, Belvončíková P, Bečka E, Strečanský T, Pastorek M, Janko J, Filová B, Babál P, Šebeková K, Borbélyová V, Gardlík R. Myeloperoxidase, extracellular DNA and neutrophil extracellular trap formation in the animal models of metabolic dysfunction-associated steatotic liver disease. World J Gastroenterol 2025; 31(27): 106166
- URL: https://www.wjgnet.com/1007-9327/full/v31/i27/106166.htm
- DOI: https://dx.doi.org/10.3748/wjg.v31.i27.106166