Myeloperoxidase, extracellular DNA and neutrophil extracellular trap formation in the animal models of metabolic dysfunction-associated steatotic liver disease

doi:10.3748/wjg.v31.i27.106166

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2025; 31(27): 106166
Published online Jul 21, 2025. doi: 10.3748/wjg.v31.i27.106166

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Figure 1 Experimental design. A: Timeline and summary of measured parameters of all three animal models; B: Visual representation of increasing dosage of thioacetamide in the thioacetamide model. BMI: Body mass index; WBC: White blood cell; LYM: Lymphocytes; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ncDNA: Nuclear DNA; mtDNA: Mitochondrial DNA; ecDNA: Extracellular DNA; MPO: Myeloperoxidase; NE: Neutrophil elastase. Graphical abstract and figures created by BioRender.com.

Citation: Feješ A, Belvončíková P, Bečka E, Strečanský T, Pastorek M, Janko J, Filová B, Babál P, Šebeková K, Borbélyová V, Gardlík R. Myeloperoxidase, extracellular DNA and neutrophil extracellular trap formation in the animal models of metabolic dysfunction-associated steatotic liver disease. World J Gastroenterol 2025; 31(27): 106166
URL: https://www.wjgnet.com/1007-9327/full/v31/i27/106166.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i27.106166