Histone deacetylases 10 as a prognostic biomarker correlates with tumor microenvironment and therapy response in colorectal cancer

Figure 6 Effect on immune checkpoints and tumor burden mutation. A: Low expression of immune checkpoints in high histone deacetylases 10 (HDAC10) group; B: HDAC10 expression negatively correlated with PD-L1 in colorectal cancer tissue microarray; C: Low tumor burden mutation score in high HDAC10 group; D: Waterfall plot for somatic mutations in different HDAC10 groups. ^aP < 0.001, ^bP < 0.01, ^cP < 0.05. HDAC10: Histone deacetylases 10.