Evaluating luminal and post-operative Crohn’s disease activity on magnetic resonance enterography: A review of radiological disease activity scores

doi:10.3748/wjg.v31.i26.107419

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Jul 14, 2025 (publication date) through Jul 14, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2025; 31(26): 107419
Published online Jul 14, 2025. doi: 10.3748/wjg.v31.i26.107419

Table 9 Operational characteristics of magnetic resonance imaging scores used to evaluate post-operative recurrence in Crohn’s disease[61,62]

MRE disease activity score	MR score	MONITOR Index
Diagnostic accuracy
Clinical recurrence	MR2/MR3	≥ 1
Reference standard	Rutgeerts score ≥ i3	Rutgeerts score ≥ i2
Sensitivity (%)	100	79-87
Specificity (%)	89	55-75
AUROC		0.80
Endoscopy index correlation
Rutgeerts score	κ = 0.673[62]
Intra-rater agreement
ICC		0.67[61]
Inter-rater agreement
ICC	κ = 0.893[62]	0.67[61]

MRE: Magnetic resonance enterography; MR: Magnetic resonance; MONITOR: Magnetic resonance imaging in Crohn’s disease to predict postoperative recurrence; ICC: Intraclass correlation coefficient; AUROC: Area under receiver operating characteristic curve.

Citation: Lo RW, Bhatnagar G, Kutaiba N, Srinivasan AR. Evaluating luminal and post-operative Crohn’s disease activity on magnetic resonance enterography: A review of radiological disease activity scores. World J Gastroenterol 2025; 31(26): 107419
URL: https://www.wjgnet.com/1007-9327/full/v31/i26/107419.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i26.107419