Evaluating luminal and post-operative Crohn’s disease activity on magnetic resonance enterography: A review of radiological disease activity scores

Table 3 Radiological parameters evaluated in the construction of magnetic resonance enterography disease activity scores in luminal Crohn’s disease[14,18,19-21,30,43]

MRE disease activity score	MaRIA[21]	Simplified MaRIA[19]	Nancy score[30]	London score[43]	CDMI[43]	Clermont score[18]	MEGS[14]	PICMI[19]	MREI[20]	C-score[21]
Mural2
Mural thickening	Yes1	Yes1	Yes1	Yes1	Yes1	Yes1	Yes1	Yes1	No	Yes1
Mural oedema	Yes1	Yes1	Yes1	Yes1	Yes1	Yes1	Yes1	No	No	No
Ulceration	Yes1	Yes1	Yes1			Yes1		Yes1	Yes1	Yes1
Mural contrast enhancement		No	Yes1	No	Yes1		Yes1	No		No
Mural relative contrast enhancement	Yes1							No	Yes1	No
Mural contrast enhancement pattern				No	No		Yes1	No
Extramural2
Mesenteric lymphadenopathy	No	No		No	No	No	Yes1		No	Yes1
Mesenteric oedema				No	Yes1		Yes1	Yes1	No
Comb sign				No	No		Yes1	Yes1	No
Fistula		No				No	Yes1
Stenosis		No						No
Abscess						No	Yes1
Prestenotic dilatation								No
Fat stranding		Yes1
Creeping fat		No								No
Haustral loss							Yes1
Conglomeration tumor
Technical aspect2
DWI hyperintensity			Yes1			No		Yes1		No
Apparent diffusion coefficient						Yes1				No
Other2
Disease length							Yes1	No		No
Differentiation between mucosa-submucosa complex and the muscularis propria			Yes1
Pseudopolyps	No
Bowel motility								No
Small bowel distortion									No

¹Radiological parameters included in the final scoring formula.

²Radiological parameters included in initial assessment but excluded from the final scoring formula.

MaRIA: Magnetic resonance index of activity; MEGS: Magnetic resonance enterography global score; CDMI: Crohn’s disease magnetic resonance imaging index; PICMI: Paediatric inflammatory Crohn’s magnetic resonance enterography index; MREI: Magnetic resonance enterography index; DWI: Diffusion-weighted imaging; MRE: Magnetic resonance enterography; C-score: Modified Clermont score.