Multi-omics analysis reveals gut microbiota-metabolite interactions and their association with liver function in autoimmune overlap syndrome

Figure 4 The correlation between the gut microbial communities and liver function. A: Redundancy analysis across three groups; B: Heatmap in overlap syndrome patients. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. RDA: Redundancy analysis; PBC: Primary biliary cholangitis; AIH: Autoimmune hepatitis; OS: Overlap syndrome; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TBIL: Total bilirubin; ALB: Albumin; GGT: Gamma-glutamyl transferase; ALP: Alkaline phosphatase; TBA: Total bile acid; TG: Triglyceride.