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©The Author(s) 2025.
World J Gastroenterol. Jul 7, 2025; 31(25): 105677
Published online Jul 7, 2025. doi: 10.3748/wjg.v31.i25.105677
Published online Jul 7, 2025. doi: 10.3748/wjg.v31.i25.105677
Table 2 Patients’ principal characteristics, management, and adverse events
No. | Gender | Age | Disease course | Clinical symptoms | Comorbidities | Past treatment | Dosage of sirolimus | Adverse events |
1 | Female | 66 | 3 years | Melena | None | Endoscopic | 2 mg, q.d. | Mouth ulcers, diarrhea |
2 | Female | 62 | 6 months | Melena | Bronchial asthma | 2 mg, q.d. | Elevated triglycerides | |
3 | Male | 49 | 14 years | Hematochezia | None | Surgery | 1 mg, q.d. | Pulmonary infection |
4 | Female | 64 | 5 years | Melena | Hypertension, bronchial asthma, mitral regurgitation | Endoscopic | 2 mg, q.d. | Diarrhea |
5 | Male | 48 | 11 months | Melena | Hypertension, pituitary tumor, multiple hepatic hemangiomas | Endoscopic | 1 mg, q.d. | None |
6 | Female | 68 | 1 year | Hematochezia | Hypertension, type 2 diabetes | 2 mg, q.d. | Mouth ulcers | |
7 | Female | 70 | 20 months | Melena | Aortic valve stenosis with regurgitation, mitral stenosis | 2 mg, q.d. | None | |
8 | Female | 39 | 9 years | Melena | None | Endoscopic, Surgery | 2 mg, q.d. | Mouth ulcers |
9 | Male | 52 | 2 years | Melena | Old cerebral infarction | 2 mg, q.d. | Mouth ulcers, rash | |
10 | Female | 73 | 8 months | Melena | Pulmonary emphysema | 1.5 mg, q.d. | None | |
11 | Female | 74 | 2 years | Melena | Pulmonary emphysema; atrial fibrillation | 1 mg, q.d. | None |
- Citation: Sun Q, Wu JC, Chen X, Li DH, Li BR, Xiao NJ, Wang XY, Tu XZ, Ning SB, Sun T. Efficacy and safety of sirolimus in the treatment of gastrointestinal angiodysplasias. World J Gastroenterol 2025; 31(25): 105677
- URL: https://www.wjgnet.com/1007-9327/full/v31/i25/105677.htm
- DOI: https://dx.doi.org/10.3748/wjg.v31.i25.105677