Rate of abnormal renal function index and related risk factors in patients with chronic hepatitis B

Table 5 Characteristics of β2 microglobulin normal and abnormal groups in treatment-naive patients with any hepatitis B virus antiviral regimen

Patient characteristics	Normal β2-MG (n = 98)	Abnormal β2-MG (n = 116)	P value
Age (years)	43.00 ± 10.96	43.34 ± 10.60	0.926
Male, %	50.0	65.5	0.026
Family history, %	53.1	44.8	0.272
Hypertension, %	4.1	6.0	0.555
Diabetes, %	2.0	6.9	0.114
Fatty liver, %	28.6	40.5	0.084
Fibrosis, %	38.8	42.2	0.676
Cirrhosis, %	4.1	6.9	0.553
ALT, U/L	38.76 ± 73.39	63.71 ± 130.14	0.017
AST, U/L	27.95 ± 23.95	40.46 ± 60.59	0.002
Total bilirubin, μmol/L	13.11 ± 6.25	13.81 ± 7.70	0.561
Direct bilirubin, μmol/L	5.01 ± 2.32	5.40 ± 3.92	0.505
Blood urea nitrogen, mmol/L	4.45 ± 1.12	4.71 ± 1.22	0.733
eGFR, mL/min	96.92 ± 18.05	92.28 ± 15.76	0.181
Cholesterol, mmol/L	4.52 ± 0.95	4.71 ± 0.90	0.540
Triglyceride, mmol/L	1.15 ± 0.53	1.3779 ± 1.33	0.008
High-density lipoprotein, mmol/L	1.41 ± 0.36	1.39 ± 0.37	0.669
Low-density lipoprotein, mmol/L	2.88 ± 0.91	2.99 ± 0.81	0.880

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; β2-MG: β2 microglobulin; eGFR: Estimated glomerular filtration rate.