Rate of abnormal renal function index and related risk factors in patients with chronic hepatitis B

doi:10.3748/wjg.v31.i25.105207

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2025; 31(25): 105207
Published online Jul 7, 2025. doi: 10.3748/wjg.v31.i25.105207

Table 3 Abnormal rate of urinary β2 microglobulin in different subgroups of treatment-experienced patients with any nucleos(t)ide

		Abnormal rate of β2-MG, %	P value
Age	> 65 years	50.0 (5/10)	0.62
Age	≤ 65 years	58.0 (160/276)	0.62
Sex	Male	62.6 (132/211)	< 0.05
Sex	Female	44.0 (33/75)	< 0.05
NUCs	ETV	54.6 (89/163)	0.47
	TDF	46.7 (7/15)
	TAF	60.5 (26/43)
	NUC switch	66.7 (40/60)
	Others	60.0 (3/5)
Duration of NUC treatment	≤ 2 years	58.3 (60/103)	0.97
	2-5 years	56.8 (63/111)
	≥ 5 years	58.3 (42/72)
HBV DNA	Positive	55.8 (24/43)	0.87
	Negative	58.1 (140/241)

β2-MG: β2 microglobulin; ETV: Entecavir; HBV: Hepatitis B virus; NUCs: nucleos(t)ide analog agents; TAF: Tenofovir alafenamide; TDF: Tenofovir disoproxil fumarate.

Citation: Gao GF, Wang XY, Yu J. Rate of abnormal renal function index and related risk factors in patients with chronic hepatitis B. World J Gastroenterol 2025; 31(25): 105207
URL: https://www.wjgnet.com/1007-9327/full/v31/i25/105207.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i25.105207