Real-world comparison of chemotherapy plus bevacizumab with or without immunotherapy as first-line therapy in colorectal cancer

doi:10.3748/wjg.v31.i24.108298

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Jun 28, 2025 (publication date) through Jun 26, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 28, 2025; 31(24): 108298
Published online Jun 28, 2025. doi: 10.3748/wjg.v31.i24.108298

Table 2 Comparison of short-term efficacy between two groups of microsatellite stable metastatic colorectal cancer

Group	Number	PR	SD	PD	ORR (%)	DCR (%)
Control group	78	18	53	7	23.08	91.03
Experimental group	25	9	15	1	36.00	96.00
χ² value	-	1.0348	0.2377	-	1.0348	-
P value	-	0.309	0.6258	0.6759¹	0.309	0.6759¹

¹Fisher’s exact test.

The control group received chemotherapy combined with bevacizumab. The experimental group received chemotherapy combined with bevacizumab and anti-programmed death 1 immunotherapy. PR: Partial response; SD: Stable disease; PD: Progressive disease; ORR: Objective response rate; DCR: Disease control rate.

Citation: Gao Z, Wang XY, Shen ZG, Liu JH, Wang XY, Wu SK, Jin X. Real-world comparison of chemotherapy plus bevacizumab with or without immunotherapy as first-line therapy in colorectal cancer. World J Gastroenterol 2025; 31(24): 108298
URL: https://www.wjgnet.com/1007-9327/full/v31/i24/108298.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i24.108298