Evaluating log odds of positive lymph nodes as a prognostic tool in differentiated gastric cancer: A retrospective study

Table 2 Baseline characteristics of patients according to the log odds of positive lymph nodes score before and after propensity score matching, n (%)

Patient characteristics	Raw cohort			PSM cohort
	LODDS1 (n = 928)	LODDS2 (n = 1175)	P value	LODDS1 (n = 736)	LODDS2 (n = 736)	P value
Sex	-	-	0.196	-	-	0.050
Male	732 (78.9)	899 (76.5)	-	580 (78.8)	564 (76.6)	-
Female	196 (21.1)	276 (23.5)	-	156 (21.2)	172 (23.4)	-
Age	-	-	0.041	-	-	0.764
< 60	320 (34.5)	456 (38.8)	-	263 (35.7)	284 (38.6)	-
≥ 60	608 (65.5)	719 (61.2)	-	473 (64.3)	452 (61.4)	-
BMI	-	-	0.072	-	-	0.934
Low	81 (8.7)	115 (9.8)	-	67 (9.1)	72 (9.7)	-
Normal	623 (67.1)	737 (62.7)	-	489 (66.4)	486 (66.0)	-
High	224 (24.2)	323 (27.5)	-	180 (24.5)	17824.3)	-
Family history	-	-	0.428	-	-	0.183
No	607 (65.5)	749 (63.7)	-	479 (65.1)	464 (63.0)	-
Yes	321 (34.5)	426 (36.3)	-	257 (34.9)	272 (37.0)	-
Smoking history	-	-	0.157	-	-	0.780
No	483 (52.0)	648 (55.1)	-	391 (53.1)	395 (53.7)	-
Yes	445 (48.0)	527 (44.9)	-	345 (46.9)	341 (46.3)	-
Drinking history	-	-	0.259	-	-	0.619
No	650 (70.0)	796 (67.7)	-	514 (69.8)	521 (70.8)	-
Yes	278 (30.0)	379 (32.3)	-	222 (30.2)	215 (29.2)	-
Surgery method	-	-	< 0.001	-	-	0.090
Open	786 (84.7)	1080 (91.9)	-	662 (89.9)	646 (87.8)	-
Laparoscopy	142 (15.3)	95 (8.1)	-	74 (10.1)	90 (12.2)	-
Pathological type	-	-	0.042	-	-	0.721
MGC	49 (5.3)	88 (7.5)	-	47 (6.4)	50 (6.8)	-
NMGC	879 (94.7)	1087 (92.5)	-	669 (93.6)	686 (93.2)	-
Nerve invasion	-	-	< 0.001	-	-	0.164
No	469 (50.5)	357 (30.4)		326 (44.3)	311 (42.3)	-
Yes	459 (49.5)	818 (69.6)		410 (55.7)	425 (57.7)	-
Vascular tumor thrombus	-	-	< 0.001	-	-	0.177
No	478 (51.5)	308 (26.2)	-	316 (42.9)	283 (38.5)	-
Yes	450 (48.5)	867 (73.8)	-	420 (57.1)	453 (61.5)	-
pTNM	-	-	< 0.001	-	-	0.086
I	72 (7.8)	6 (0.5)	-	25 (3.4)	6 (0.8)	-
II	241 (26.0)	72 (6.1)	-	173 (23.5)	63 (8.6)	-
III	615 (66.3)	1097 (93.4)	-	538 (73.1)	667 (90.6)	-
CEA	-	-	< 0.001	-	-	0.176
Low	731 (79.1)	840 (71,5)	-	575 (78.1)	508 (69.0)	-
High	194 (20.9)	335 (28.5)	-	161 (21.9)	228 (31.0)	-
AFP	-	-	0.296	-	-	0.110
Low	873 (94.1)	1092 (92.9)		694 (94.3)	685 (93.1)	-
High	55 (5.9)	83 (7.1)		42 (5.7)	51 (6.9)	-
CA19-9	-	-	< 0.001	-	-	0.051
Low	732 (78.9)	793 (67.5)	-	563 (76.5)	504 (68.5)	-
High	196 (21.1)	382 (32.5)	-	173 (23.5)	232 (31.5)	-
CA72-4	-	-	< 0.001	-	-	0.408
Low	760 (81.9)	881 (75.0)	-	594 (80.7)	564 (76.6)	-
High	168 (18.1)	294 (25.0)	-	142 (19.3)	172 (23.4)	-
CA125	-	-	0.053	-	-	0.956
Low	878 (94.6)	1087 (92.5)	-	695 (94.4)	685 (93.1)	-
High	50 (5.4)	88 (7.5)	-	41 (5.6)	51 (6.9)	-
CA242	-	-	< 0.001	-	-	0.120
Low	782 (84.3)	878 (74.7)	-	603 (81.9)	555 (75.4)	-
High	146 (15.7)	297 (25.3)	-	133 (18.1)	181 (24.6)	-
Differentiation	-	-	< 0.001	-	-	-
Well	9 (1.0)	6 (0.6)	-	-	-	-
Moderate	629 (67.7)	655 (55.7)	-	-	-	-
Poor	290 (31.3)	514 (43.7)	-	-	-	-
NPLN	-	-	< 0.001	-	-	-
NPLN1	892 (96.1)	272 (23.1)	< 0.001	-	-	-
NPLN2	36 (3.9)	903 (76.90)	-	-	-	-
NTLN	-	-	0.014	-	-	-
NTLN1	613 (66.1)	835 (71.1)	-	-	-	-
NTLN2	315 (33.9)	340 (28.9)	-	-	-	-
LNR
LNR1	928 (100)	0	< 0.001	-	-	-
LNR2	0	1175 (100)	-	-	-	-
pN	-	-	< 0.001	-	-	-
N1+N2	603 (65.0)	22 (1.9)	-	-	-	-
N3a+N3b	325 (35.0)	1153 (98.1)	-	-	-	-

PSM: Propensity score matching; BMI: Body mass index; MGC: Mucinous gastric adenocarcinoma; NMGC: Non-mucinous gastric adenocarcinoma; pTNM: Pathological tumor-node-metastasis; NPLN: Number of positive lymph nodes; NTLN: Number of total lymph nodes; LNR: Lymph node ratio; LODDS: Log odds of positive lymph nodes; pN: American Joint Committee on Cancer pathologic N stage; CA: Carbohydrate antigen; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen.