Recent advances and challenges in colorectal cancer: From molecular research to treatment

doi:10.3748/wjg.v31.i21.106964

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Jun 7, 2025 (publication date) through Jun 30, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2025; 31(21): 106964
Published online Jun 7, 2025. doi: 10.3748/wjg.v31.i21.106964

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Figure 7 The intestinal crypt is composed of a specialized microenvironment. Created with MedPeer (medpeer.cn). Copyright permission has been obtained in the Supplementary material. Intestinal stem cells drive crypt renewal and give rise to transamplifying cells, whereas Paneth cells secrete critical niche factors, such as Wnt, which is essential for maintaining the stem cell niche.

Citation: Qi GX, Zhao RX, Gao C, Ma ZY, Wang S, Xu J. Recent advances and challenges in colorectal cancer: From molecular research to treatment. World J Gastroenterol 2025; 31(21): 106964
URL: https://www.wjgnet.com/1007-9327/full/v31/i21/106964.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i21.106964