Retrospective Study
Copyright ©The Author(s) 2025.
World J Gastroenterol. May 21, 2025; 31(19): 104563
Published online May 21, 2025. doi: 10.3748/wjg.v31.i19.104563
Table 3 Univariate and multivariate analyses of factors associated with gastroesophageal variceal bleeding in patients with Budd-Chiari syndrome and gastroesophageal varices
Variables
Univariate cox regression
Multivariate cox regression
HR (95%CI)
P value
HR (95%CI)
P value
Age0.994 (0.968-1.020)0.646
Sex3.621 (1.686-7.777)0.001
Hepatic encephalopathy0.712 (0.098-5.166)0.737
Diabetes0.535 (0.130-2.209)0.388
Portal vein thrombosis3.329 (1.486-7.460)0.003
IVC or HV thrombosis0.696 (0.295-1.645)0.409
Invasive treatment to relieve hepatic venous outflow obstruction0.127 (0.070-0.230)< 0.0010.123 (0.048-0.318)<0.001
Use of anticoagulant medication3.408 (1.056-10.994)0.0408.905 (2.296-34.534)0.002
Ascites1.798 (1.001-3.229)0.050
Portal vein diameter (mm)1.003 (0.915-1.099)0.953
Spleen thickness (mm)1.041 (1.015-1.068)0.002
White blood cell (× 109/L)1.071 (0.946-1.221)0.271
Red blood cell (× 1012/L)0.563 (0.388-0.818)0.003
Hemoglobin (g/L)0.976 (0.965-0.986)< 0.0010.974 (0.955-0.994)0.012
Platelet (× 109/L)0.988 (0.979-0.997)0.006
Sodium (mmol/L)0.828 (0.773-0.887)< 0.001
Creatinine (µmol/L)1.025 (1.014-1.037)< 0.001
Aspartate aminotransferase (U/L)1.009 (1.001-1.017)0.020
Gamma-glutamyl transferase (U/L)1.000 (0.998-1.002)0.864
Alkaline phosphatase (U/L)1.004 (1.002-1.007)0.002
Albumin0.899 (0.861-0.939)< 0.001
Direct bilirubin1.012 (1.007-1.016)< 0.001
Prothrombin time1.080 (1.047-1.113)< 0.001
BCS type0.081
Mixed type vs HV type0.501 (0.265-0.945)0.033
IVC type vs HV type0.450 (0.149-1.355)0.156
Child< 0.001
B vs A1.408 (0.706-2.808)0.311
C vs A14.353 (6.881-29.937)< 0.001