Rapid pathologic grading-based diagnosis of esophageal squamous cell carcinoma via Raman spectroscopy and a deep learning algorithm

Table 2 Analysis of peak positions and assignment in Raman spectra during low-health and high-low progressions

Progression type	Change direction	Raman shift, cm-1	Band assignments
Low-health	Increase	891	Lauric acid
		1078	v(C-C) of lipids
		1095	DNA, symmetric PO, stretching vibration
		1132	Cytochrome c
		1171	Acetoacetate
		1216	Amide III and CH2 wagging
		1295	Amide III delta (CH)2
		1369	Thymine
		1417	CH2 stretch
		1440	Lipin
		1596-1616	Phenylalanine C = C
		1618	v(C = C) of porphyrins
High-low	Decrease	891	Lauric acid
		1004	vs(C-C) ring breathing of phenylalanine
		1078	v(C-C) of lipids
		1095	DNA, symmetric PO, stretching vibration
		1132	Cytochrome c
		1171	Acetoacetate
		1295	Amide III delta (CH)2
		1315	Glycerol
		1369	Thymine
		1417	CH2 stretch
		1448-1468	CH3 deformation
		1618	v(C = C) of porphyrins