Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation

Table 4 Univariate and multivariate analyses of the factors associated with the results of needle-knife papillotomy

Variables	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Age
> 70	0.988 (0.960-1.017)	0.408
≤ 70	Reference
Sex
Female	0.938 (0.389-2.261)	0.887
Male	Reference
Choledocholithiasis
Yes	1.256 (0.505-3.128)	0.642
No	Reference
Malignant biliary stricture
Yes	0.941 (0.365-2.424)	0.9
No	Reference
Benign biliary stricture
Yes	0.714 (0.087-5.848)	0.753
No	Reference
CBD diameter
≤ 6 mm	1.018 (0.914-1.134)	0.745
> 6 mm	Reference
Periampullary diverticulum
Yes	3.009 (1.216-7.448)	0.017	4.235 (1.541-11.637)	0.005
No	Reference		Reference
Impacted stone in the ampulla of Vater
Yes	0.840 (0.181-3.899)	0.824
No	Reference
Surgically altered anatomy
Yes	7.857 (1.051-58.75)	0.045	9.111 (0.942-88.120)	0.056
No	Reference
Endoscopists
D + E	1.914 (0.690-5.310)	0.212
B + C	1.179 (0.483-2.876)	0.717
A	Reference
Significant bleeding during NKP
Yes	7.454 (2.066-26.886)	0.002	5.022 (1.280–19.707)	0.021
No	Reference		Reference
PS before NKP
Yes	0.325 (0.115-0.915)	0.033	0.284 (0.092–0.871)	0.028
No	Reference		Reference

NKP: Needle-knife papillotomy; OR: Odds ratio; CI: Confidence interval; CBD: Common bile duct; PS: Pancreatic stent.