Correlation between the neuroendocrine axis, microbial species, inflammatory response, and gastrointestinal symptoms in irritable bowel syndrome

Table 5 Correlation of neuroendocrine axis with intestinal microbiota and inflammatory response in irritable bowel syndrome patients

	ACTH		COR
	r	P value	r	P value
Bacteroides	0.378	< 0.001	0.392	< 0.001
Lactobacillus	-0.359	< 0.001	-0.336	< 0.001
Bifidobacterium	-0.315	< 0.001	-0.348	< 0.001
Clostridium	-0.333	< 0.001	-0.329	< 0.001
Fusobacterium	-0.362	< 0.001	-0.347	< 0.001
IL-6	0.482	< 0.001	0.392	< 0.001
IL-8	0.513	< 0.001	0.496	< 0.001
IL-10	0.396	< 0.001	0.423	< 0.001

ACTH: Adrenocorticotropic hormone; COR: Cortisol.