Histopathological impact of SARS-CoV-2 on the liver: Cellular damage and long-term complications

Table 1 Liver injury in patients with coronavirus disease 2019 infection, n (%)

Ref.	Condition	Present
Lagana et al[28]	Lobular necroinflammation	20/40 (50)
Sonzogni et al[45]	Inflammation and fibrosis	24/48 (50)
Chu et al[32]	Inflammation and necrosis	24/24 (100)
Schmit et al[43]	Centrilobular necrosis	11/13 (85)
	Lobular inflammation	8/13 (62)
Duarte-Neto et al[51]	Centrilobular/midzonal necrosis	49/75 (65)
Sweed et al[33]	Inflammation and necrosis	1/1 (100)
Vishwajeet et al[44]	Lobular inflammation	13/20 (65)
	Kupffer cell hypertrophy	17/20 (85)
Yurdaisik et al[48]	Extensive necrosis	2/7 (29)
	Patchy necrosis	4/7 (57)
Canillas et al[52]	Fibrosis	8/14 (57)
Ramos-Rincon et al[47]	Necrosis	5/39 (13)
Santana et al[49]	Necrosis	26/27 (96)
	Lobular inflammation	2/27 (7)
Pesti et al[29]	Fibrosis	78/150 (52)
	Necrosis	103/145 (71)
	Chronic inflammation	63/146 (43)

Inflammation cell types varied between neutrophils, monocytes, and lymphocytes.