Development of a nomogram for predicting liver transplantation prognosis in hepatocellular carcinoma

Table 3 Univariate analysis for overall survival and recurrence-free survival

Variable	n	Overall survival (%)			P value	Recurrence-free survival (%)			P value
		1 yr	3 yr	5 yr		1 yr	3 yr	5 yr
Number of tumour					0.054				0.006
Single tumor	79	0.87	0.78	0.75		0.78	0.77	0.75
Multiple tumors	81	0.88	0.64	0.57		0.69	0.55	0.54
Maximum tumor diameter (cm)					< 0.001				< 0.001
> 5	48	0.79	0.50	0.43		0.58	0.45	-
≤ 5	112	0.92	0.80	0.73		0.80	0.75	0.73
Total tumor diameter (cm)					< 0.001				< 0.001
> 8	46	0.74	0.43	0.38		0.43	0.37	0.34
≤ 8	114	0.93	0.82	0.76		0.86	0.78	-
Vascular invasion					< 0.001				< 0.001
Yes	42	0.69	0.50	0.37		0.50	0.33	0.31
No	118	0.90	0.79	0.74		0.82	0.78	-
Lymph node metastasis					0.098				0.129
Yes	20	0.75	0.60	0.49		0.60	0.50	-
No	140	0.92	0.72	0.68		0.75	0.68	0.67
Membrane invasion					0.001				< 0.001
Yes	59	0.78	0.54	0.50		0.76	0.52	0.46
No	101	0.92	0.78	0.72		0.95	0.82	0.76
Microsatellite lesions					0.002				0.001
Yes	79	0.83	0.60	0.52		0.65	0.53	0.51
No	81	0.92	0.81	0.77		0.81	0.79	0.77
AFP					< 0.001				< 0.001
≤ 400	115	0.90	0.82	0.78		0.86	0.79	-
> 400	45	0.82	0.42	0.33		0.42	0.31	0.28
GP73					0.001				< 0.001
≤ 222	126	0.91	0.76	0.73		0.78	0.73	0.72
> 222	34	0.76	0.52	0.34		0.55	0.38	-
DCP					< 0.001				< 0.001
≤ 26	92	0.91	0.82	0.81		0.85	0.82	0.81
> 26	68	0.83	0.55	0.44		0.57	0.42	0.41
CK18-M65 (U/L)					< 0.001				< 0.001
≤ 1066	95	0.93	0.84	0.81		0.85	0.80	0.80
> 1066	65	0.80	0.52	0.41		0.56	0.43	0.41
CK18-M30 (U/L)					< 0.001				<0.001
≤ 530	95	0.94	0.86	0.83		0.86	0.83	0.82
> 530	65	0.78	0.49	0.39		0.54	0.40	0.39
MC					< 0.001				< 0.001
Yes	64	0.97	0.86	0.82		0.88	0.83	0.81
No	96	0.82	0.61	0.55		0.63	0.54	0.53
UCSF					< 0.001				< 0.001
Yes	77	0.97	0.89	0.85		0.90	0.87	0.85
No	83	0.79	0.54	0.46		0.57	0.47	0.45
Hangzhou					< 0.001				< 0.001
Yes	109	0.95	0.83	0.78		0.86	0.81	0.80
No	51	0.80	0.45	0.37		0.47	0.33	0.31

CK18: Cytokeratin-18; GP73: Golgi protein 73.