Taurine attenuates activation of hepatic stellate cells by inhibiting autophagy and inducing ferroptosis

Figure 1 Effects of taurine on extracellular matrix. A: Detection of effect of taurine on the viability of hepatic stellate cells by Cell Counting Kit-8 method; B: Detection of the effect of taurine on mRNA expression of fibronectin 1, collagen I, and α-SMA by reverse transcription-polymerase chain reaction; C: Detection of effect of taurine on protein expression of fibronectin 1, collagen Ι, and α-SMA by Western blot. Data are expressed as the mean ± SD. ^aP < 0.05 vs control, ^bP < 0.01 vs control, ^cP < 0.05 vs platelet-derived growth factor-BB (PDGF-BB), ^dP < 0.01 vs PDGF-BB. PDGF-BB: Platelet-derived growth factor-BB.