Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer

Figure 3 Abundance of butyrate-producing bacteria is decreased in mice treated with Fusobacteriumnucleatum. A and B: The 16S rDNA sequencing results showed that the abundance of fecal butyric acid-producing bacteria (Lac_Rosebaria and Clostridium) was lower than those of the control group in mice treated with Fusobacterium nucleatum by gavage (n = 12 for each group). Each bar represents the content of Clostridium (A) or Lactobacillus (B) in the feces of mice in the treatment group.