Bayesian network-based survival prediction model for patients having undergone post-transjugular intrahepatic portosystemic shunt for portal hypertension

Table 2 Univariate survival analysis of patients having undergone transjugular intrahepatic portosystemic shunt surgery for portal hypertension

Variable	HR	95%CI	P value	Variable	HR	95%CI	P value
Age (yr)				< 40	1.00
< 60	1.00			≥ 40	0.39	0.16-0.97	0.043
≥ 60	3.64	2.24-5.89	< 0.001	AST (U/L)
Etiology of cirrhosis				≤ 40	1.00
Hepatitis B virus	1.00			> 40	1.73	1.07-2.81	0.026
Hepatitis C virus	0.85	0.20-3.53	0.820	ALP (U/L)
Alcoholic	3.23	1.74-5.99	< 0.001	≤ 135	1.00
Autoimmune	1.51	0.67-3.41	0.317	> 135	2.60	1.5-4.51	< 0.001
Others	1.34	0.64-2.78	0.434	TBIL (µmol/L)
Hypertension				≤ 28	1.00
No	1.00			> 28	2.65	1.64-4.29	< 0.001
Yes	3.75	1.89-7.44	< 0.001	PA (mg/L)
Indications for TIPS				< 150	1.00
Variceal bleeding	1.00			≥ 150	0.38	0.16-0.88	0.024
Refractory ascites	2.23	1.14-4.36	0.020	WBC (109/L)
Ascites				< 3.5	1.00
None	1.00			3.5-9.5	1.70	1.04-2.76	0.033
Small	0.61	0.31-1.22	0.164	> 9.5	1.49	0.46-4.88	0.507
Moderate to large	2.51	1.48-4.26	< 0.001	Child-Pugh grade
Post-TIPS PVP (mmH2O)				A	1.00
≤ 23.1	1.00			B	2.09	1.16-3.76	0.014
> 23.1	2.85	1.30-6.23	0.009	C	5.12	2.53-10.37	< 0.001
Na (mmol/L)				MELD score
< 137	1.00			Low risk	1.00
≥ 137	0.54	0.33-0.89	0.016	Medium risk	2.33	1.18-4.58	0.014
ALB (g/L)				High risk	5.98	2.38-15.05	< 0.001

Post-PVP: Postoperative portal vein pressures; Na: Sodium; ALB: Albumin; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; TBIL: Total bilirubin; PA: Prealbumin; WBC: White blood cell count; MELD: Model for end-stage liver disease.