Inhibitory effect of sulindac against chemically-induced primary colonic tumors by N-methyl-N-nitrosourea in mice

Table 4 Effect of sulindac on the volume of the colorectal tumor induced by N-methyl-N-nitrosourea

	Experiment one		Experiment two
	Sulindacgroup	Control group	Control group	Sulindacgroup
Median tumor diameter (mm)1
< 1	5	5	8	6
1.1-1.5	4	1	4	5
1.6-2.0	4	2	5	4
2.1-2.5	3	1	2	3
2.6-2.9	2	0	1	1
> 3.0	1	0	1	1
Median tumor volume (mm3)2
1-3	5	4	7	7
4-6	4	3	3	3
7-9	3	1	4	4
10-13	2	1	2	3
14-16	1	0	2	1
17-20	2	0	1	0
21-24	1	0	1	1
> 25	1	0	1	1

¹Wilcoxon rank test, Experiment one: μ = 8.155, P < 0.01; Experiment two: μ = 1.464, P > 0.05.

²Wilcoxon rank test, Experiment one: μ = 5.500, P < 0.01; Experiment two: μ = 1.333, P > 0.05.