Observational Study
Copyright ©The Author(s) 2023.
World J Gastroenterol. Feb 14, 2023; 29(6): 1090-1108
Published online Feb 14, 2023. doi: 10.3748/wjg.v29.i6.1090
Table 2 Overall survival rates by background characteristics from 2000 to 2018
CharacteristicsChina
United States
1-yr, % (95%CI)
3-yr, % (95%CI)
5-yr, % (95%CI)
1-yr, % (95%CI)
3-yr, % (95%CI)
5-yr, % (95%CI)
Total
Period of diagnosis
1 (2000-2003)75.0 (63.2-89.0)54.5 (41.7-71.4)47.7 (35.0-65.0)58.4 (55.3-61.7)40.7 (37.7-44.0)36.2 (33.2-39.4)
2 (2004-2008)80.1 (74.5-86.1)59.7 (52.9-67.3)54.1 (47.4-61.9)58.1 (55.4-61.0)42.3 (39.6-45.2)38.4 (35.7-41.3)
3 (2009-2013)76.7 (72.3-81.3)57.1 (52.1-62.6)51.6 (46.6-57.2)60.8 (58.1-63.6)44.0 (41.2-46.9)39.7 (37.0-42.6)
4 (2014-2018)88.6 (85.1-92.3)66.5 (60.8-72.7)61.6(58.9-64.4)43.0 (39.9-46.4)
Race
Chinese81.4 (78.9-84.1)60.9 (57.6-64.3)52.3 (48.8-56.0)66.0 (58.1-75.1)52.9 (44.4-62.9)42.9 (34.4-53.5)
White59.7 (58.1-61.5)41.7 (40.0-43.6)37.8 (36.0-39.6)
Black58.0 (54.3-61.8)42.7 (39.0-46.7)38.2 (34.6-42.3)
Others59.4 (55.6-63.5)43.3 (39.4-47.6)37.2 (33.3-41.6)
Gender
Male82.2 (78.7-85.8)61.5 (57.1-66.2)53.6 (49.0-58.7)57.0 (55.0-59.0)39.6 (37.6-41.7)34.8 (32.8-36.9)
Female80.6 (76.9-84.5)60.2 (55.5-65.3)50.7 (45.7-56.2)63.0 (61.0-65.1)46.2 (44.1-48.4)42.2 (40.1-44.4)
Primary tumor location
Proximal 76.7 (69.8-84.2)47.7 (39.8-57.2)42.7 (34.7-52.4)59.0 (56.0-62.2)35.8 (32.8-39.1)30.5 (27.5-33.7)
Distal84.5 (81.8-87.3)66.3 (62.8-70.1)57.4 (53.5-61.5)64.6 (62.5-66.7)48.0 (45.8-50.4)42.9 (40.6-45.3)
Differentiation
Well100.0 (100.0-100.0)100.0 (100.0-100.0)85.7 (63.3-100.0)92.5 (88.9-96.2)83.3 (78.0-89.0)78.8 (72.6-85.6)
Moderate90.4 (84.7-96.6)76.1 (67.6-85.6)66.3 (56.4-78.0)72.3 (67.9-76.9)50.1 (45.2-55.5)44.6 (39.6-50.1)
Poor/Undifferentiated87.7 (84.8-90.7)69.6 (65.4-74.0)61.6 (57.0-66.5)48.3 (46.3-50.5)25.7 (23.9-27.6)19.9 (18.2-21.8)
Linitis plastica
Yes57.1 (39.5-82.8)14.3 (5.0-40.7)4.8 (0.7-32.2)49.5 (37.8-65.0)14.8 (7.6-29.0)12.3 (5.8-26.4)
No83.9 (81.4-86.6)68.7 (65.4-72.2)63.8 (60.2-67.5)60.0 (58.6-61.4)43.1 (41.6-44.6)38.6 (37.1-40.1)
Signet ring cell carcinoma
Yes91.0 (87.9-94.2)80.3 (75.8-85.0)76.9 (72.1-82.1)49.5 (37.8-65.0)14.8 (7.6-29.0)12.3 (5.8-26.4)
No90.2 (86.7-93.8)75.1 (70.0-80.6)70.8 (65.2-76.8)60.0 (58.6-61.4)43.1 (41.6-44.6)38.6 (37.1-40.1)
pTNM stage (AJCC TNM 8th)
I100.0 (100.0-100.0)99.4 (98.4-100.0)99.4 (98.4-100.0)91.5 (89.3-93.8)86.4 (83.6-89.2)83.4 (80.2-86.6)
II97.1 (94.3-99.9)83.6 (77.5-90.3)69.8 (61.9-78.7)84.2 (80.4-88.2)68.4 (63.4-73.8)61.0 (55.5-67.0)
III83.5 (79.4-87.9)54.9 (49.3-61.0)42.6 (37.0-49.2)74.8 (70.9-78.8)41.0 (36.5-46.1)29.6 (25.3-34.7)
IV51.2 (43.8-59.7)17.4 (12.3-24.8)9.9 (6.0-16.3)29.7 (27.5-32.1)10.4 (8.8-12.1)7.1 (5.7-8.7)
Surgery
Yes89.6 (87.3-92.0)72.4 (69.0-76.0)63.4 (59.5-67.5)82.6 (80.9-84.3)61.2 (59.0-63.5)53.6 (51.3-56.1)
No58.4 (51.8-65.9)33.4 (26.9-41.5)28.7 (22.2-37.0)43.2 (41.3-45.1)29.1 (27.4-31.0)27.0 (25.3-28.9)
Chemotherapy
Yes89.1 (85.8-92.6)67.0 (61.9-72.6)52.7 (47.1-59.1)55.9 (54.1-57.8)32.7 (31.0-34.6)27.4 (25.7-29.2)
No76.8 (73.3-80.4)57.2 (53.1-61.6)51.9 (47.7-56.5)66.4 (64.2-68.6)59.2 (56.9-61.6)56.2 (53.9-58.7)
Lymphadenectomy
Yes90.8 (88.4-93.2)77.7 (74.3-81.3)73.7 (69.9-77.6)70.9 (67.9-73.9)39.4 (36.2-42.8)29.2 (26.1-32.6)
No64.0 (58.3-70.3)41.4 (35.4-48.5)35.1 (29.0-42.5)57.2 (55.6-58.8)43.7 (42.1-45.4)40.7 (39.1-42.4)
Lymphadenectomy with at least 15 lymph nodes
Yes91.8 (89.3-94.3)79.9 (76.2-83.3)76.2 (72.2-80.6)77.3 (73.7-81.1)43.4 (39.4-48.6)32.4 (28.1-37.2)
No86.5 (80.4-93.1)69.0 (60.9-78.3)64.1 (55.6-73.8)63.0 (58.4-67.9)34.0 (29.6-39.1)25.3 (21.2-30.2)