Chemical components and protective effects of Atractylodes japonica Koidz. ex Kitam against acetic acid-induced gastric ulcer in rats

Figure 5 Effect of Atractylodesjaponica on gastric ulcer-associated genes in acid-induced gastric tissues (n = 8). A-D: The mRNA levels of epidermal growth factor receptor, Zonula Occludens-1, nuclear factor kappa-B p65, IkappaBalpha in gastric tissues were analysed by real-time reverse transcription polymerase chain reaction. ^bP < 0.01 vs normal group; ^cP < 0.05 and ^dP < 0.01 vs model group. EGFR: Epidermal growth factor receptor; ZO-1: Zonula Occludens-1; NF-κB: Nuclear factor kappa-B; IκBα: IkappaBalpha; NG: Normal group; MG: Model group; OG: Omeprazole group; LA: Low dose group of Atractylodes japonica; MA: Middle dose group of Atractylodes japonica; HA: High dose group of Atractylodes japonica.