Radiomics model based on contrast-enhanced computed tomography to predict early recurrence in patients with hepatocellular carcinoma after radical resection

Table 2 Univariate and multivariate Cox regression analyses of clinicopathologic characteristics for recurrence-free survival in training cohort with hepatocellular carcinoma

Variable	Univariate analysis			Multivariate analysis
	HR	95%CI	P value	HR	95%CI	P value
Rad-score (high vs low) (n)	4.08	2.64-6.24	< 0.001	3.86	2.41-6.16	< 0.001
HBsAg (present vs absent) (n)	1.81	0.97-3.39	0.063
Cirrhosis (present vs absent) (n)	1.84	0.75-4.52	0.183
MVI (present vs absent) (n)	1.83	1.24-2.71	0.002	1.20	0.77-1.85	0.418
AFP (> 200 vs ≤ 200) (ng/mL)	1.73	1.16-2.58	0.007	1.52	1.00-2.30	0.048
Tumor size (cm)	1.05	1.01-1.09	0.005	1.00	0.94-1.04	0.621
Platelets (× 109/L)	1.00	1.00-1.00	0.160
GGT (U/L)	1.02	1.04-1.02	0.034	1.01	1.01-1.00	0.333
DB (mg/dL)	1.00	1.00-1.01	0.928
ALBI	0.96	0.64-1.44	0.838

HR: Hazard ratio; CI: Confidence interval; HBsAg: Hepatitis B surface antigen; MVI: Microvascular invasion; AFP: Alpha fetoprotein; GGT: Gamma-glutamyl transpeptidase; DB: Direct bilirubin; ALBI: Albumin-bilirubin.