Prediction of lymph node metastasis in early gastric signet-ring cell carcinoma: A real-world retrospective cohort study

Table 5 Clinical characteristics in patients with pure signet-ring cell carcinoma and mixed signet-ring cell carcinoma

Variable	Pure SRCC	Mixed SRCC	P value
	n = 95, n (%)	n = 154, n (%)
Age (yr)			0.037
≤ 65	70 (73.68)	91 (59.09)
> 65	25 (26.32)	63 (40.91)
Gender			0.131
Male	46 (48.42)	87 (56.49)
Female	49 (51.58)	67 (43.51)
Location			0.255
Cardia	4 (4.21)	7 (4.55)
Fundus	2 (2.11)	3 (1.95)
Body	13 (13.68)	30 (19.48)
Antrum	51 (53.68)	78 (50.65)
Angle	25 (26.32)	36 (23.38)
Macroscopic type			0.152
Protruded (0-I)	1 (1.05)	2 (1.30)
Elevated (0-IIa)	5 (5.26)	6 (3.90)
Flat (0-IIb)	23 (24.21)	29 (18.83)
Depressed (0-IIc)	65 (68.42)	113 (73.38)
Excavated (0-III)	1 (1.05)	4 (2.60)
Tumor size (cm)			0.126
≤ 2	60 (63.16)	79 (51.30)
> 2	35 (36.84)	75 (48.70)
Ulceration			0.051
UL (-)	75 (78.95)	100 (64.94)
UL (+)	20 (21.05)	54 (35.06)
Depth of invasion			< 0.001
M	71 (74.74)	78 (50.65)
SM	24 (25.26)	76 (49.35)
LVI			0.002
Absence	95 (100.00)	136 (88.31)
Presence	0 (0.00)	18 (11.69)
Perineural invasion			0.420
Absence	94 (98.95)	148 (96.10)
Presence	1 (1.05)	6 (3.90)
LNM			< 0.001
Absence	87 (91.58)	100 (64.94)
Presence	8 (8.42)	54 (35.06)

SRCC: Signet-ring cell carcinoma; M: Mucosal; SM: Submucosal; LNM: Lymph node metastasis; LVI: Lymphovascular invasion; UL (-): Ulcer or ulcer scar is absent; UL (+): Ulcer or ulcer scar is present.