Review
Copyright ©The Author(s) 2023.
World J Gastroenterol. Jun 14, 2023; 29(22): 3385-3399
Published online Jun 14, 2023. doi: 10.3748/wjg.v29.i22.3385
Table 1 Summary of Clostridioides difficile diagnostic tests
Test     
Abbreviation
Sensitivity
Specificity
Turn-around time
Target substance
Culture-based
Cell cytotoxicity neutralisation assayCCTNHighHigh< 24 hToxins
Toxigenic cultureTCHighLow1> 3 dC. difficile vegetative cells or spores
DNA-based
Nucleic acid amplification test2NAATHighLow/moderate< 4 hToxin genes
Protein-based
Glutamate dehydrogenaseGDH-EIAHighLow1< 2 hC. difficile antigens
Toxin A and B enzyme immunoassaysEIALowModerate< 2 hToxins