Fibroblast growth factor 15, induced by elevated bile acids, mediates the improvement of hepatic glucose metabolism after sleeve gastrectomy

Figure 2 Sleeve gastrectomy increased the bile acids levels and hepatic glycogen content. A: The concentration of total bile acid; B and C: The levels of chenodeoxycholic acid, DCA, lithocholic acid, and cholic acid in serum and portal vein, respectively; D: The glycogen content in liver at week 12 postoperation in SHAM and SG group. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001; SG vs SHAM group. BA: Bile acid; TBA: Total bile acid; SG: Sleeve gastrectomy; CDCA: Chenodeoxycholic acid; LCA: Lithocholic acid; CA: Cholic acid.