Alcohol-related hepatitis: A review article

doi:10.3748/wjg.v29.i17.2551

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Gastroenterol. May 7, 2023; 29(17): 2551-2570
Published online May 7, 2023. doi: 10.3748/wjg.v29.i17.2551

Table 3 Clinical trials under investigation

Drugs	Mechanisms	Clinical trials
Anakinra and Canakinumab	Reduce hepatic inflammation	NCT01809132[121], NCT04072822[122], NCT03775109[123]
N-acetyl cysteine, S-adenosyl methionine (SAM-E)	Reduce oxidative stress	NCT03069300[124], NCT00851981[125], NCT02024295[126]
DUR-928	Epigenetic modulation of lipid homeostasis, inflammation, cell survival, tissue regeneration	NCT03432260[127], NCT03917407[128]
Granulocyte colony stimulating growth factors, interleukin-22 and obeticholic acid	Boosts liver regeneration	NCT02442180[129], NCT03703674[130], NCT04066179[131], NCT02655510[132], NCT01918462[133], NCT02039219[134]
Rifaximin, zinc supplementation, bovine colostrum, probiotics, and fecal microbiota transplant	Targets the gut-liver axis	NCT02116556[135], NCT02485106[136], NCT01968382[137], NCT02473341[138], NCT01922895[139], NCT02335632[140], NCT02458079[141], NCT03091010[142], NCT03827772[143]

Citation: Chaudhry H, Sohal A, Iqbal H, Roytman M. Alcohol-related hepatitis: A review article. World J Gastroenterol 2023; 29(17): 2551-2570
URL: https://www.wjgnet.com/1007-9327/full/v29/i17/2551.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i17.2551