Anti-inflammatory effect and antihepatoma mechanism of carrimycin

Figure 1 Experimental flow chart. The distribution and metabolism of carrimycin in various mouse tissues and organs were assessed by hyphenated to liquid chromatography, and the effect of carrimycin on inflammatory factors in these tissues and organs was detected by enzyme-linked immunosorbent assay. Reverse molecular docking technology was used to screen for the targets of carrimycin, and the predicted target was enriched and analyzed to obtain data on the related diseases. Then, the key targets and associated pathways for the treatment of liver cancer were analyzed by network pharmacology. HPLC: Hyphenated to liquid chromatography; ELISA: Enzyme-linked immunosorbent assay; GO: Gene Ontology; KEEG: Kyoto Encyclopedia of Genes and Genomes; PPI: Protein-protein interaction.