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©The Author(s) 2023.
World J Gastroenterol. Apr 7, 2023; 29(13): 2015-2033
Published online Apr 7, 2023. doi: 10.3748/wjg.v29.i13.2015
Published online Apr 7, 2023. doi: 10.3748/wjg.v29.i13.2015
Table 2 Characteristics of liver disease in six-time intervals
| Parameter | 2015-2016 | 2017 | 2018 | 2019 | 2020 | 2021 |
| Number of patients | 1199 | 827 | 573 | 438 | 199 | 341 |
| GT, n (%) | ||||||
| 1 | 17 (1.4) | 22 (2.7) | 15 (2.6) | 7 (1.6) | 1 (0.5) | 7 (2.1) |
| 1a | 21 (1.8) | 17 (2.1) | 10 (1.7) | 10 (2.3) | 9 (4.5) | 8 (2.3) |
| 1b | 1070 (89.2) | 652 (78.8) | 420 (73.3) | 291 (66.4) | 125 (62.8) | 247 (72.4) |
| 2 | 0 | 0 | 1 (0.2) | 3 (0.7) | 0 | 3 (0.9) |
| 3 | 56 (4.7) | 103 (12.4) | 109 (19.0) | 111 (25.3) | 60 (30.2) | 63 (18.5) |
| 4 | 35 (2.9) | 33 (4.0) | 17 (3) | 16 (3.7) | 4 (2) | 13 (3.8) |
| 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | 0 | 0 | 1 (0.2) | 0 | 0 | 0 |
| Child-Pugh class, n (%) | ||||||
| A | 1033 (86.2) | 724 (87.6) | 521 (90.9) | 397 (90.7) | 176 (88.4) | 285 (83.6) |
| B | 118 (9.8) | 77 (9.3) | 47 (8.2) | 36 (8.2) | 18 (9.1) | 49 (14.3) |
| C | 9 (0.7) | 1 (0.1) | 2 (0.4) | 1 (0.2) | 1 (0.5) | 3 (0.9) |
| No data | 39 (3.3) | 25 (3.0) | 3 (0.5) | 4 (0.9) | 4 (2.0) | 4 (1.2) |
| MELD score, n (%) | ||||||
| < 15 | 1072 (89.4) | 757 (91.5) | 529 (92.3) | 414 (94.5) | 188 (94.5) | 319 (93.5) |
| 15-18 | 45 (3.8) | 28 (3.4) | 29 (5.1) | 12 (2.8) | 3 (1.5) | 14 (4.1) |
| 19-20 | 11 (0.9) | 12 (1.5) | 5 (0.9) | 4 (0.9) | 2 (1) | 4 (1.2) |
| > 20 | 13 (1.1) | 4 (0.5) | 7 (1.2) | 3 (0.7) | 2 (1) | 2 (0.6) |
| No data | 58 (4.8) | 26 (3.1) | 3 (0.5) | 5 (1.1) | 4 (2) | 2 (0.6) |
| History of hepatic decompensation, n (%) | ||||||
| Ascites | 124 (10.3) | 65 (7.8) | 64 (11.2) | 26 (5.9) | 15 (7.5) | 47 (13.8) |
| Encephalopathy | 33 (2.8) | 15 (1.8) | 19 (3.3) | 4 (0.9) | 2 (1) | 7 (2.1) |
| Documented esophageal varices, n (%) | 375 (31.3) | 202 (24.4) | 127 (22.2) | 85 (19.4) | 38 (19.1) | 58 (17) |
| Hepatic decompensation at baseline, n (%) | ||||||
| Moderate ascites-responded to diuretics | 47 (3.9) | 30 (3.6) | 29 (5.1) | 22 (5) | 10 (5) | 29 (8.5) |
| Tense ascites-not responded to diuretics | 3 (0.3) | 0 | 2 (0.3) | 0 | 0 | 3 (0.9) |
| Encephalopathy | 30 (2.5) | 13 (1.6) | 7 (1.2) | 7 (1.6) | 2 (1) | 9 (2.6) |
| HCC history, n (%) | 57 (4.8) | 30 (3.6) | 19 (3.3) | 15 (3.4) | 7 (3.5) | 19 (5.6) |
| OLTx history, n (%) | 23 (1.9) | 4 (0.5) | 1 (0.2) | 1 (0.2) | 0 | 1 (0.3) |
| HBV coinfection (HBsAg+), n (%) | 12 (1) | 12 (1.5) | 12 (2.1) | 8 (1.8) | 3 (1.5) | 6 (1.8) |
| HIV coinfection, n (%) | 13 (1.1) | 16 (1.9) | 16 (2.8) | 28 (6.4) | 9 (4.5) | 10 (2.9) |
- Citation: Brzdęk M, Zarębska-Michaluk D, Rzymski P, Lorenc B, Kazek A, Tudrujek-Zdunek M, Janocha-Litwin J, Mazur W, Dybowska D, Berak H, Parfieniuk-Kowerda A, Klapaczyński J, Sitko M, Sobala-Szczygieł B, Piekarska A, Flisiak R. Changes in characteristics of patients with hepatitis C virus-related cirrhosis from the beginning of the interferon-free era. World J Gastroenterol 2023; 29(13): 2015-2033
- URL: https://www.wjgnet.com/1007-9327/full/v29/i13/2015.htm
- DOI: https://dx.doi.org/10.3748/wjg.v29.i13.2015