Risk factors predict microscopic extranodal tumor deposits in advanced stage III colon cancer patients

Table 1 Baseline characteristics of N1c group and non-N1c group, n (%)

Item	N1c	Non-N1c	P value
Sample size (n)	19	136
Gender			0.08
Male	13 (68.4)	64 (47.1)
Female	6 (31.6)	72 (52.9)
Mean age (yr)	66.79	65.17	0.09
BMI (kg/m2)	22.77	23.41	0.15
Habit of smoking	8 (42.1)	46 (33.8)	0.48
Habit of alcoholic drinking	4 (21.1)	13 (9.6)	0.13
Hypertension	6 (31.6)	46 (33.8)	0.85
Diabetes mellitus	4 (21.1)	29 (21.3)	0.98
Neutrophil to Lymphocyte ratio	4.33	4.62	0.42
CEA (mg/dL)	12.83	18.23	0.62
CA 19-9 (mg/dL)	23.61	29.14	0.20
Tumor characteristics
Location			0.27
Right colon	6 (9)	61 (91)
Left colon	13 (14.8)	75 (85.2)
T stage			0.90
T1	1 (5.3)	5 (3.7)
T2	1 (5.3)	12 (8.8)
T3	16 (84.2)	110 (80.9)
T4a	0 (0)	4 (2.9)
T4b	1 (5.3)	5 (3.7)
Mean tumor size (cm)	4.24	4.8	0.98
Tumor type			0.26
Polypoid	8 (42.1)	76 (55.9)
Ulcerative	11 (57.9)	60 (44.1)
Tumor grade			0.62
Well	0	5 (100)
Moderate	16 (13.3)	104 (86.7)
Poor	3 (10.0)	27 (90.0)
EGFR	17 (89.5)	117 (86.0)	0.68
Lymphovascular invasion	3 (15.8)	53 (39.0)	0.049

95%CI: 95% confidence interval; BMI: Body mass index; NLR: Neutrophil to lymphocyte ratio; CEA: Carcinoembryonic antigen; CA 19-9: Carbohydrate antigen 19-9.