Systemic treatment for metastatic colorectal cancer

Table 1 Modifiable and non-modifiable risk factors and preventive factors for colorectal cancer

	Modifiable	Non-modifiable
Risk factors	Excess body fat	Family history of CRC
	Sedentary life-style	Advanced polyps
	Westernized diet	Polyposis syndrome (FAP, MAP)
	Processed meats	Lynch syndrome (HNPCC)
	Red meats	Black people
		Older age
		Male
Preventive factors	High fiber diet	Female
	Whole grain diet
	No alcohol
	No smoking

CRC: Colorectal cancer; FAP: Familial adenomatous polyposis; HNPCC: Hereditary non-polyposis colorectal cancer; MAP: MUTYH-associated polyposis.