Bladder-colon chronic cross-sensitization involves neuro-glial pathways in male mice

Figure 1 Assessment of visceromotor response to colorectal distensions. A-C: Changes in intracolonic pressure in response to isobaric colorectal distensions (15, 30, 45 and 60 mmHg) after intravesical injections of acetic acid (0.75%) vs saline (NaCl 0.9%) in mice at 1 h (A), 1 d (B) and 7 d (C) after injections, with details of the comparison at 60 mmHg of distension on the right. n = 8 mice per group. ^aP < 0.05 and ^bP < 0.001. Variability in the results is represented by the standard error of the mean (area under the curve ± standard error of the mean). AUC: Area under the curve.