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Copyright ©The Author(s) 2022.
World J Gastroenterol. Dec 28, 2022; 28(48): 6900-6908
Published online Dec 28, 2022. doi: 10.3748/wjg.v28.i48.6900
Figure 2
Figure 2 The diagram assuming the relationship between gene mutations and gastric carcinogenesis. Superficial gastric tumors can be roughly divided into two types by specific gene mutations: The APC mutation type and the TP53 mutation type. APC-type tumors have low malignancy and develop into low-grade dysplasia, whereas TP53-type tumors have high malignancy and are considered cancerous even if small. JGCA: Japanese Gastric Cancer Association; HGD: High-grade dysplasia; LGD: Low-grade dysplasia.